- R&D 100 Awards
As the Director of Translational Biology at Sanford Burnham Prebys Medical Discovery Institute in Orlando, Florida, Siobhan Malany, PhD, leads an interdisciplinary team of biologists and medicinal chemists and a diverse drug discovery portfolio for non-profit and commercial partners for the purposes of translation medical discoveries. She also provides assay development and scientific consultation to investigators to compete for various funding opportunities. Siobhan is a key contributor in the development of toxicological platforms using human iPSC-derived stem cells, a bicoastal collaboration funded by the USAF.
Prior to joining Sanford Burnham Prebys in 2010, she spent eight years in the San Diego biotechnology industry. At Tanabe Research Laboratories, a subsidiary of Mitsubishi Tanabe Pharma, she led the biochemistry group with a focus on targets in metabolic disease and autoimmune therapeutic areas. At Neurocrine Biosciences, she led pharmacology lead optimization efforts for G-protein coupled receptor programs in CNS and contributed to the IND for a novel sleep drug.
Her early career research focused on establishing quantitative, mechanistic pharmacological structure-function models of protein inhibition. She was a Center for Biocatalysis and Bioprocessing PhD fellow in bioorganic chemistry at the University of Iowa and was a Tobacco-Related Disease Research postdoctoral fellow in pharmacology at the University of CA, San Diego. She was recipient of the Alexander von Humboldt Fellowship to extend her studies at the Max-Planck Institute for Brain Research, Frankfurt, Germany.
Siobhan is also the founder of Sanford Burnham Prebys’ first spin-off company, micro-gRx, Inc., which studies the effects of microgravity on human muscle myocytes.