- R&D 100 Awards
The current gold standard for the evaluation of cardiac MRI function is 2D cine imaging with standardized protocols and slice orientations providing accurate and reproducible quantitative values for ejection fraction (EF), stroke volume, end-systolic and end-diastolic volume. Nearly every cardiac MRI examination includes a 2D cine scan for the assessment of left-ventricular (LV) function. Conventionally, a stack of 2D slices in the short-axis orientation covering the left ventricle is acquired for this purpose in multiple breath-holds. However, the recovery time between breath-holds extends the total duration of the exam, and acquisitions in several consecutive breath-holds may be too challenging for severely ill patients. With Compressed Sensing Cardiac Cine, LV function can be assessed within a single breath-hold. With the high speed of Compressed Sensing Cardiac Cine, cardiac MRI has become accessible and easier for entire patient groups, in particular those with breath-hold difficulties and cardiac arrhythmias. In the past, Cardiac MRI scans were highly time-consuming with poor patient acceptance or non-diagnostic in such groups due to the low diagnostic quality of the images, which is no longer the case with the new application.