- R&D 100 Awards
The ANDE system performs fully automated generation and interpretation of DNA fingerprints in less than two hours outside of the lab. The system is designed for the non-technical user, making rapid DNA identification accessible to any law enforcement member. Conventional laboratory technology can take months to years to process DNA evidence. Millions of samples are not submitted or even collected because the results come too late to have a real impact on the investigation. The result of these delays is that is takes longer to solve crimes—and, most importantly, those responsible remain on the street and can commit more crimes. ANDE employs a disposable plastic chip and a fully integrated instrument to perform DNA fingerprinting. Four basic steps are involved. First, DNA is isolated from the crime scene sample and then a total of 27 STR chromosomal regions are copied using a process called the Polymerase Chain Reaction. Next, the sizes of the copied DNA fragments are determined and then the size pattern of the copied STR fragments is interpreted, generating the DNA fingerprint. In the laboratory, these four steps require hundreds of manual manipulations.